Version 5.4
Mus musculus Gene: Zfat
Summary
InnateDB Gene IDBG-147216.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zfat
Gene Name zinc finger and AT hook domain containing
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000022335
Encoded Proteins
IDBP-531967
zinc finger and AT hook domain containing
IDBP-540571
zinc finger and AT hook domain containing
IDBP-535176
zinc finger and AT hook domain containing
IDBP-540604
zinc finger and AT hook domain containing
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000066827:
This gene encodes a protein that likely binds DNA and functions as a transcriptional regulator involved in apoptosis and cell survival. This gene resides in a susceptibility locus for autoimmune thyroid disease (AITD) on chromosome 8q24. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:68083766-68258856
Strand Reverse strand
Band D2
Transcripts
ENSMUST00000162054 ENSMUSP00000125732
ENSMUST00000162173 ENSMUSP00000124974
ENSMUST00000160248 ENSMUSP00000125257
ENSMUST00000159430 ENSMUSP00000124420
ENSMUST00000161139
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
GO:0006351 transcription, DNA-templated
GO:0030097 hemopoiesis
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0060712 spongiotrophoblast layer development
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000066827
View Gene Order
ENSBTAG00000017731
Not yet available
Cross-References
SwissProt Q7TS63
TrEMBL
UniProt Splice Variant
Entrez Gene 380993
UniGene Mm.309526
RefSeq NM_001145888 XM_006521124 NM_198644 XM_006521125
OMIM
CCDS CCDS49623 CCDS49624
HPRD
IMGT
MGI ID MGI:2681865
MGI Symbol Zfat
EMBL BC053930 EU221277
GenPept AAH53930 ABY67968
RNA Seq Atlas 380993

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca