Version 5.4
Mus musculus Gene: Tra2b
Summary
InnateDB Gene IDBG-148073.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tra2b
Gene Name transformer 2 beta homolog (Drosophila)
Synonyms 5730405G21Rik; D16Ertd266e; Sfrs10; SIG-41; Silg41; TRA2beta
Species Mus musculus
Ensembl Gene ENSMUSG00000022858
Encoded Proteins
IDBP-148075
transformer 2 beta homolog (Drosophila)
IDBP-534539
transformer 2 beta homolog (Drosophila)
IDBP-535705
transformer 2 beta homolog (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136527:
This gene encodes a nuclear protein which functions as sequence-specific serine/arginine splicing factor which plays a role in mRNA processing, splicing patterns, and gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:22244549-22266005
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000023564 ENSMUSP00000023564
ENSMUST00000161286 ENSMUSP00000124846
ENSMUST00000162413 ENSMUSP00000123782
ENSMUST00000161774
ENSMUST00000159946
ENSMUST00000160579
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 58 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 58 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003729 mRNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0000398 mRNA splicing, via spliceosome
GO:0048026 positive regulation of mRNA splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000136527
View Gene Order
ENSBTAG00000001697
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03040
Spliceosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03040
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.210352 Mm.392922 Mm.405060 Mm.431896
RefSeq NM_009186 XM_006521877
OMIM
CCDS CCDS37297
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca