Version 5.4
Mus musculus Gene: Mtus1
Summary
InnateDB Gene IDBG-150350.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mtus1
Gene Name mitochondrial tumor suppressor 1
Synonyms AI481402; ATBP135; Atip1; B430010I23Rik; B430305I03Rik; C85752; Cctsg1-440; MD44; mKIAA1288; MTSG1
Species Mus musculus
Ensembl Gene ENSMUSG00000045636
Encoded Proteins
IDBP-150352
mitochondrial tumor suppressor 1
IDBP-150354
mitochondrial tumor suppressor 1
IDBP-150356
mitochondrial tumor suppressor 1
IDBP-401383
mitochondrial tumor suppressor 1
IDBP-401382
mitochondrial tumor suppressor 1
IDBP-541004
mitochondrial tumor suppressor 1
IDBP-536147
mitochondrial tumor suppressor 1
IDBP-532987
mitochondrial tumor suppressor 1
IDBP-533481
mitochondrial tumor suppressor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129422:
This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:40990914-41133726
Strand Reverse strand
Band A4
Transcripts
ENSMUST00000059115 ENSMUSP00000059503
ENSMUST00000051379 ENSMUSP00000053554
ENSMUST00000093534 ENSMUSP00000091252
ENSMUST00000118835 ENSMUSP00000112626
ENSMUST00000117735 ENSMUSP00000113082
ENSMUST00000135194
ENSMUST00000155626
ENSMUST00000131965 ENSMUSP00000121605
ENSMUST00000155174
ENSMUST00000142936
ENSMUST00000127665
ENSMUST00000143853 ENSMUSP00000116339
ENSMUST00000145860 ENSMUSP00000119440
ENSMUST00000155055 ENSMUSP00000119163
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007049 cell cycle
GO:0010758 regulation of macrophage chemotaxis
GO:0071375 cellular response to peptide hormone stimulus
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000129422
View Gene Order
ENSBTAG00000039682
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.149438 Mm.401655 Mm.475369
RefSeq NM_001005863 NM_001005864 NM_001005865 NM_001286413 XM_006509241
OMIM
CCDS CCDS40328 CCDS40329 CCDS40330
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca