Homo sapiens Gene: MTUS1
Summary
InnateDB Gene IDBG-8742.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTUS1
Gene Name microtubule associated tumor suppressor 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000129422
Encoded Proteins
microtubule associated tumor suppressor 1
microtubule associated tumor suppressor 1
microtubule associated tumor suppressor 1
microtubule associated tumor suppressor 1
microtubule associated tumor suppressor 1
microtubule associated tumor suppressor 1
microtubule associated tumor suppressor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:17643795-17800917
Strand Reverse strand
Band p22
Transcripts
ENST00000262102 ENSP00000262102
ENST00000381869 ENSP00000371293
ENST00000381861 ENSP00000371285
ENST00000297488 ENSP00000297488
ENST00000517413
ENST00000520196 ENSP00000431016
ENST00000519263 ENSP00000430167
ENST00000518889
ENST00000518792
ENST00000523471
ENST00000518713
ENST00000522757
ENST00000521772
ENST00000524371
ENST00000517818
ENST00000524044
ENST00000523183
ENST00000519066
ENST00000521635
ENST00000522149
ENST00000521882
ENST00000518138
ENST00000517721
ENST00000518975
ENST00000523718
ENST00000518755
ENST00000518891
ENST00000544260 ENSP00000445738
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0010758 regulation of macrophage chemotaxis
GO:0071375 cellular response to peptide hormone stimulus
Cellular Component
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0005815 microtubule organizing center
GO:0005819 spindle
GO:0005874 microtubule
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.690946 Hs.7946
RefSeq NM_001001924 NM_001001925 NM_001001931 NM_001166393 NM_020749 XM_005273577 XM_005273578 XM_005273579 XM_005273580 XM_005273581 XM_005273582
HUGO
OMIM
CCDS CCDS43716 CCDS43717 CCDS43718 CCDS43719 CCDS55204
HPRD 11376
IMGT
EMBL
GenPept
RNA Seq Atlas