Homo sapiens Gene: MTUS1 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-8742.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | MTUS1 | ||||||||||||||||||
Gene Name | microtubule associated tumor suppressor 1 | ||||||||||||||||||
Synonyms | |||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000129422 | ||||||||||||||||||
Encoded Proteins |
microtubule associated tumor suppressor 1
microtubule associated tumor suppressor 1
microtubule associated tumor suppressor 1
microtubule associated tumor suppressor 1
microtubule associated tumor suppressor 1
microtubule associated tumor suppressor 1
microtubule associated tumor suppressor 1
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 8:17643795-17800917 | ||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||
Band | p22 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | |||||||||||||||||||
UniGene | Hs.690946 Hs.7946 | ||||||||||||||||||
RefSeq | NM_001001924 NM_001001925 NM_001001931 NM_001166393 NM_020749 XM_005273577 XM_005273578 XM_005273579 XM_005273580 XM_005273581 XM_005273582 | ||||||||||||||||||
HUGO | |||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | CCDS43716 CCDS43717 CCDS43718 CCDS43719 CCDS55204 | ||||||||||||||||||
HPRD | 11376 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | |||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||