Version 5.4
| Mus musculus Gene: Pde1c | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-150470.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | Pde1c | ||||||||||||||||||
| Gene Name | phosphodiesterase 1C | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||
| Ensembl Gene | ENSMUSG00000004347 | ||||||||||||||||||
| Encoded Proteins |
phosphodiesterase 1C
phosphodiesterase 1C
phosphodiesterase 1C
phosphodiesterase 1C
phosphodiesterase 1C
phosphodiesterase 1C
phosphodiesterase 1C
phosphodiesterase 1C
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154678:
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM, Oct 2009] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 6:56069821-56369634 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | B3 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Innate Immune System pathway
Signaling by ERBB2 pathway
PLCG1 events in ERBB2 signaling pathway
Disease pathway
Signaling by GPCR pathway
Ca-dependent events pathway
Signaling by FGFR in disease pathway
PLC-gamma1 signalling pathway
Immune System pathway
EGFR interacts with phospholipase C-gamma pathway
Downstream signal transduction pathway
Downstream signaling of activated FGFR pathway
CaM pathway pathway
Signaling by EGFR pathway
Phospholipase C-mediated cascade pathway
Cam-PDE 1 activation pathway
Signalling by NGF pathway
Signaling by PDGF pathway
DAG and IP3 signaling pathway
NGF signalling via TRKA from the plasma membrane pathway
Opioid Signalling pathway
Calmodulin induced events pathway
Signal Transduction pathway
Signaling by FGFR pathway
PLC beta mediated events pathway
G-protein mediated events pathway
Signaling by EGFR in Cancer pathway
DAP12 interactions pathway
DAP12 signaling pathway
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| KEGG |
Olfactory transduction pathway
Calcium signaling pathway pathway
Purine metabolism pathway
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| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Cam-PDE 1 activation pathway
Calmodulin induced events pathway
CaM pathway pathway
DAG and IP3 signaling pathway
DAP12 signaling pathway
DAP12 interactions pathway
PLC-gamma1 signalling pathway
EGFR interacts with phospholipase C-gamma pathway
Signaling by EGFR pathway
PLC beta mediated events pathway
Opioid Signalling pathway
PLCG1 events in ERBB2 signaling pathway
Signaling by ERBB2 pathway
Phospholipase C-mediated cascade pathway
Signaling by FGFR pathway
Downstream signal transduction pathway
Signaling by PDGF pathway
Signaling by FGFR in disease pathway
Signalling by NGF pathway
Signaling by EGFR in Cancer pathway
Downstream signaling of activated FGFR pathway
Signaling by GPCR pathway
Innate Immune System pathway
Signal Transduction pathway
G-protein mediated events pathway
Immune System pathway
NGF signalling via TRKA from the plasma membrane pathway
Ca-dependent events pathway
Disease pathway
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| KEGG |
Olfactory transduction pathway
Purine metabolism pathway
Calcium signaling pathway pathway
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| INOH |
Purine nucleotides nucleosides metabolism pathway
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| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| UniGene | Mm.5145 | ||||||||||||||||||
| RefSeq | NM_001025568 NM_001159952 NM_001159953 NM_001159955 NM_001159956 NM_001159957 NM_001159960 NM_011054 XM_006505733 XM_006505735 | ||||||||||||||||||
| OMIM | |||||||||||||||||||
| CCDS | CCDS20170 CCDS51783 CCDS51784 CCDS51785 CCDS51786 CCDS51787 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| MGI ID | |||||||||||||||||||
| MGI Symbol | |||||||||||||||||||
| EMBL | |||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||||