Version 5.4
Mus musculus Gene: Faf2
Summary
InnateDB Gene IDBG-153931.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Faf2
Gene Name Fas associated factor family member 2
Synonyms 2210404D11Rik; AI462440; mKIAA0887; Ubxd8
Species Mus musculus
Ensembl Gene ENSMUSG00000025873
Encoded Proteins
IDBP-153933
Fas associated factor family member 2
IDBP-542216
Fas associated factor family member 2
IDBP-538806
Fas associated factor family member 2
IDBP-541278
Fas associated factor family member 2
IDBP-538832
Fas associated factor family member 2
IDBP-538269
Fas associated factor family member 2
IDBP-538536
Fas associated factor family member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113194:
The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of AD patients. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:54621784-54664068
Strand Forward strand
Band B1
Transcripts
ENSMUST00000026991 ENSMUSP00000026991
ENSMUST00000126071 ENSMUSP00000121182
ENSMUST00000135015 ENSMUSP00000117945
ENSMUST00000135232 ENSMUSP00000123026
ENSMUST00000137413 ENSMUSP00000116612
ENSMUST00000124752 ENSMUSP00000121606
ENSMUST00000153894 ENSMUSP00000120594
ENSMUST00000141915
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 69 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 69 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0031625 ubiquitin protein ligase binding
GO:0035473 lipase binding
GO:0043130 ubiquitin binding
GO:0055102 lipase inhibitor activity
Biological Process
GO:0006986 response to unfolded protein
GO:0034389 lipid particle organization
GO:0043086 negative regulation of catalytic activity
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005811 lipid particle
GO:0034098 Cdc48p-Npl4p-Ufd1p AAA ATPase complex
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000113194
View Gene Order
ENSBTAG00000017744
Not yet available
Cross-References
SwissProt Q3TDN2
TrEMBL D3YUP4
UniProt Splice Variant
Entrez Gene 76577
UniGene Mm.194459 Mm.408988 Mm.474945
RefSeq NM_178397 XM_006517452 XM_006517453
OMIM
CCDS CCDS36668
HPRD
IMGT
MGI ID MGI:1923827
MGI Symbol Faf2
EMBL AC155262 AC162526 AK122394 AK151617 AK170111 BC046817
GenPept AAH46817 BAC65676 BAE30554 BAE41569
RNA Seq Atlas 76577

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca