Version 5.4
Homo sapiens Gene: FAF2
Summary
InnateDB Gene IDBG-58895.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAF2
Gene Name Fas associated factor family member 2
Synonyms ETEA; UBXD8; UBXN3B
Species Homo sapiens
Ensembl Gene ENSG00000113194
Encoded Proteins
IDBP-58897
Fas associated factor family member 2
IDBP-474039
Fas associated factor family member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of AD patients. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:176447628-176510074
Strand Forward strand
Band q35.2
Transcripts
ENST00000261942 ENSP00000261942
ENST00000510730 ENSP00000424146
ENST00000506061
ENST00000510446
ENST00000504983
ENST00000513627
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 84 experimentally validated interaction(s) in this database.
Experimentally validated
Total 84 [view]
Protein-Protein 84 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0031625 ubiquitin protein ligase binding
GO:0035473 lipase binding
GO:0043130 ubiquitin binding
GO:0055102 lipase inhibitor activity
Biological Process
GO:0006986 response to unfolded protein
GO:0034389 lipid particle organization
GO:0043086 negative regulation of catalytic activity
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005811 lipid particle
GO:0034098 Cdc48p-Npl4p-Ufd1p AAA ATPase complex
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025873
View Gene Order
ENSBTAG00000017744
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.484242 Hs.619215
RefSeq NM_014613
HUGO
OMIM
CCDS CCDS34296
HPRD 16870
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca