Version 5.4
Bos taurus Gene: FAF2
Summary
InnateDB Gene IDBG-645098.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAF2
Gene Name FAS-associated factor 2
Synonyms UBX8; UBXD8
Species Bos taurus
Ensembl Gene ENSBTAG00000017744
Encoded Proteins
IDBP-697784
FAS-associated factor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113194:
The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of AD patients. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:39268354-39337797
Strand Forward strand
Band
Transcripts
ENSBTAT00000057329 ENSBTAP00000052507
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 66 interaction(s) predicted by orthology.
Predicted by orthology
Total 66 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0031625 ubiquitin protein ligase binding
GO:0035473 lipase binding
GO:0043130 ubiquitin binding
GO:0055102 lipase inhibitor activity
Biological Process
GO:0006986 response to unfolded protein
GO:0034389 lipid particle organization
GO:0043086 negative regulation of catalytic activity
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005811 lipid particle
GO:0034098 Cdc48p-Npl4p-Ufd1p AAA ATPase complex
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000113194
View Gene Order
ENSMUSG00000025873
View Gene Order
Cross-References
SwissProt Q2HJD0
TrEMBL
UniProt Splice Variant
Entrez Gene 767948
UniGene Bt.26767
RefSeq NM_001077020 XM_005209155 XM_005209156
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105572
GenPept AAI05573
RNA Seq Atlas 767948

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca