Version 5.4
Mus musculus Gene: Slirp
Summary
InnateDB Gene IDBG-160379.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slirp
Gene Name SRA stem-loop interacting RNA binding protein
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000021040
Encoded Proteins
IDBP-160381
RIKEN cDNA 1810035L17 gene
IDBP-532015
RIKEN cDNA 1810035L17 gene
IDBP-531860
RIKEN cDNA 1810035L17 gene
IDBP-540010
RIKEN cDNA 1810035L17 gene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119705:
Steroid receptor RNA activator (SRA, or SRA1; MIM 603819) is a complex RNA molecule containing multiple stable stem-loop structures that functions in coactivation of nuclear receptors. SLIRP interacts with stem-loop structure-7 of SRA (STR7) and modulates nuclear receptor transactivation (Hatchell et al., 2006 [PubMed 16762838]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:87443896-87452206
Strand Forward strand
Band D2
Transcripts
ENSMUST00000077462 ENSMUSP00000076673
ENSMUST00000161023 ENSMUSP00000125341
ENSMUST00000160488 ENSMUSP00000124174
ENSMUST00000160880 ENSMUSP00000125727
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000961 negative regulation of mitochondrial RNA catabolic process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007286 spermatid development
GO:0007338 single fertilization
GO:0030317 sperm motility
GO:0070584 mitochondrion morphogenesis
Cellular Component
GO:0001669 acrosomal vesicle
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0030529 ribonucleoprotein complex
GO:0036126 sperm flagellum
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000119705
View Gene Order
ENSBTAG00000008135
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 380773
UniGene
RefSeq NM_026958
OMIM
CCDS CCDS36503
HPRD
IMGT
MGI ID MGI:1916394
MGI Symbol Slirp
EMBL
GenPept
RNA Seq Atlas 380773

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca