Version 5.4
Mus musculus Gene: Ngfrap1
Summary
InnateDB Gene IDBG-173089.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ngfrap1
Gene Name nerve growth factor receptor (TNFRSF16) associated protein 1
Synonyms AL033356; Bex3; DXWsu67e; Gcap27; Nade
Species Mus musculus
Ensembl Gene ENSMUSG00000046432
Encoded Proteins
IDBP-173091
nerve growth factor receptor (TNFRSF16) associated protein 1
IDBP-254573
nerve growth factor receptor (TNFRSF16) associated protein 1
IDBP-254575
nerve growth factor receptor (TNFRSF16) associated protein 1
IDBP-716912
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166681:
Gene Information
Type Protein coding
Genomic Location Chromosome X:136270253-136271978
Strand Forward strand
Band F1
Transcripts
ENSMUST00000053540 ENSMUSP00000063039
ENSMUST00000113113 ENSMUSP00000108738
ENSMUST00000113112 ENSMUSP00000108737
ENSMUST00000178632 ENSMUSP00000136952
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005123 death receptor binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166681
View Gene Order
ENSBTAG00000006026
Not yet available
Pathways
NETPATH
REACTOME
REACT_204413
Cell death signalling via NRAGE, NRIF and NADE pathway
REACT_210754
NADE modulates death signalling pathway
REACT_248921
Signalling by NGF pathway
REACT_188257
Signal Transduction pathway
REACT_210847
p75 NTR receptor-mediated signalling pathway
KEGG
mmu04722
Neurotrophin signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_13526
NADE modulates death signalling pathway
REACT_11061
Signalling by NGF pathway
REACT_13776
p75 NTR receptor-mediated signalling pathway
REACT_111102
Signal Transduction pathway
REACT_13720
Cell death signalling via NRAGE, NRIF and NADE pathway
REACT_211402
Cell death signalling via NRAGE, NRIF and NADE pathway
REACT_214353
Signal Transduction pathway
REACT_207066
Signalling by NGF pathway
REACT_224179
NADE modulates death signalling pathway
REACT_218183
p75 NTR receptor-mediated signalling pathway
KEGG
hsa04722
Neurotrophin signaling pathway pathway
INOH
PID NCI
p75ntrpathway
p75(NTR)-mediated signaling
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.413418
RefSeq NM_001110233 NM_001110234 NM_009750
OMIM
CCDS CCDS30419 CCDS53194
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca