Version 5.4
Mus musculus Gene: Bag5
Summary
InnateDB Gene IDBG-173485.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bag5
Gene Name BCL2-associated athanogene 5
Synonyms 1600025G07Rik; 4930405J06Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000049792
Encoded Proteins
IDBP-173487
BCL2-associated athanogene 5
IDBP-537567
BCL2-associated athanogene 5
IDBP-540421
BCL2-associated athanogene 5
IDBP-539366
BCL2-associated athanogene 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166170:
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:111709488-111713257
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000054636 ENSMUSP00000051049
ENSMUST00000160576 ENSMUSP00000125183
ENSMUST00000160825 ENSMUSP00000123839
ENSMUST00000162953 ENSMUSP00000124861
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0031625 ubiquitin protein ligase binding
GO:0051087 chaperone binding
Biological Process
GO:0031397 negative regulation of protein ubiquitination
GO:0051444 negative regulation of ubiquitin-protein transferase activity
GO:0061084 negative regulation of protein refolding
GO:0070997 neuron death
GO:0090083 regulation of inclusion body assembly
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
GO:0016234 inclusion body
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166170
View Gene Order
ENSBTAG00000017361
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.44239
RefSeq NM_027404 XM_006516215 XM_006516216 XM_006516217 XM_006516218
OMIM
CCDS CCDS26185
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca