Version 5.4
Mus musculus Gene: Zcrb1
Summary
InnateDB Gene IDBG-176703.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zcrb1
Gene Name zinc finger CCHC-type and RNA binding motif 1
Synonyms 2700088M22Rik; Madp-1
Species Mus musculus
Ensembl Gene ENSMUSG00000022635
Encoded Proteins
IDBP-176705
zinc finger CCHC-type and RNA binding motif 1
IDBP-538512
zinc finger CCHC-type and RNA binding motif 1
IDBP-532909
zinc finger CCHC-type and RNA binding motif 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139168:
Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:93386097-93398334
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000076070 ENSMUSP00000075441
ENSMUST00000162160 ENSMUSP00000124549
ENSMUST00000160407
ENSMUST00000159723
ENSMUST00000159105
ENSMUST00000161955
ENSMUST00000161409 ENSMUSP00000125442
ENSMUST00000159719
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0008270 zinc ion binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005654 nucleoplasm
GO:0005689 U12-type spliceosomal complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000139168
View Gene Order
ENSBTAG00000019119
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.293181
RefSeq NM_026025 XM_006521295
OMIM
CCDS CCDS27766
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca