Version 5.4
Mus musculus Gene: Nosip
Summary
InnateDB Gene IDBG-181398.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nosip
Gene Name nitric oxide synthase interacting protein
Synonyms 2310061K06Rik; CGI-25
Species Mus musculus
Ensembl Gene ENSMUSG00000003421
Encoded Proteins
IDBP-181400
nitric oxide synthase interacting protein
IDBP-265838
nitric oxide synthase interacting protein
IDBP-265840
nitric oxide synthase interacting protein
IDBP-533989
nitric oxide synthase interacting protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000142546:
The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:45062429-45078503
Strand Forward strand
Band B3
Transcripts
ENSMUST00000003513 ENSMUSP00000003513
ENSMUST00000107830 ENSMUSP00000103461
ENSMUST00000107829 ENSMUSP00000103460
ENSMUST00000141908
ENSMUST00000143901
ENSMUST00000150609 ENSMUSP00000114617
ENSMUST00000125189
ENSMUST00000132359
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0043086 negative regulation of catalytic activity
GO:0051001 negative regulation of nitric-oxide synthase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000142546
View Gene Order
ENSBTAG00000014450
Not yet available
Pathways
NETPATH
REACTOME
REACT_226405
NOSIP mediated eNOS trafficking pathway
REACT_204801
eNOS activation and regulation pathway
REACT_188937
Metabolism pathway
REACT_208364
Metabolism of nitric oxide pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_12510
NOSIP mediated eNOS trafficking pathway
REACT_12389
eNOS activation and regulation pathway
REACT_12508
Metabolism of nitric oxide pathway
REACT_111217
Metabolism pathway
REACT_216663
NOSIP mediated eNOS trafficking pathway
REACT_226352
eNOS activation and regulation pathway
REACT_220341
Metabolism of nitric oxide pathway
REACT_219139
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.272139
RefSeq NM_001163684 NM_025533
OMIM
CCDS CCDS21228 CCDS52242
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca