Version 5.4
Bos taurus Gene: NOSIP
Summary
InnateDB Gene IDBG-640586.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NOSIP
Gene Name Nitric oxide synthase-interacting protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014450
Encoded Proteins
IDBP-692867
Nitric oxide synthase-interacting protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000142546:
The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:56443747-56455743
Strand Reverse strand
Band
Transcripts
ENSBTAT00000019215 ENSBTAP00000019215
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0043086 negative regulation of catalytic activity
GO:0051001 negative regulation of nitric-oxide synthase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000142546
View Gene Order
ENSMUSG00000003421
View Gene Order
Pathways
NETPATH
REACTOME
REACT_216663
NOSIP mediated eNOS trafficking pathway
REACT_226352
eNOS activation and regulation pathway
REACT_220341
Metabolism of nitric oxide pathway
REACT_219139
Metabolism pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_12510
NOSIP mediated eNOS trafficking pathway
REACT_12389
eNOS activation and regulation pathway
REACT_12508
Metabolism of nitric oxide pathway
REACT_111217
Metabolism pathway
REACT_226405
NOSIP mediated eNOS trafficking pathway
REACT_204801
eNOS activation and regulation pathway
REACT_188937
Metabolism pathway
REACT_208364
Metabolism of nitric oxide pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q3SWY5
TrEMBL
UniProt Splice Variant
Entrez Gene 511234
UniGene Bt.10405
RefSeq NM_001075502
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC104600
GenPept AAI04601
RNA Seq Atlas 511234

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca