Version 5.4
Mus musculus Gene: Glra2
Summary
InnateDB Gene IDBG-185152.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Glra2
Gene Name glycine receptor, alpha 2 subunit
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000018589
Encoded Proteins
IDBP-185154
glycine receptor, alpha 2 subunit
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101958:
The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:165129017-165327393
Strand Reverse strand
Band F5
Transcripts
ENSMUST00000058787 ENSMUSP00000060827
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005230 extracellular ligand-gated ion channel activity
GO:0016594 glycine binding
GO:0016934 extracellular-glycine-gated chloride channel activity
GO:0022824 transmitter-gated ion channel activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0007218 neuropeptide signaling pathway
GO:0007416 synapse assembly
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0034707 chloride channel complex
GO:0045211 postsynaptic membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000101958
View Gene Order
ENSBTAG00000017209
Not yet available
Pathways
NETPATH
REACTOME
REACT_198558
Ligand-gated ion channel transport pathway
REACT_262350
Ion channel transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
KEGG
mmu04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_25387
Ligand-gated ion channel transport pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt Q7TNC8
TrEMBL Q3UTL8
UniProt Splice Variant
Entrez Gene 237213
UniGene Mm.113877
RefSeq NM_183427 XM_006528833 XM_006528834 XM_006528835 XM_006528836
OMIM
CCDS CCDS41206
HPRD
IMGT
MGI ID MGI:95748
MGI Symbol Glra2
EMBL AK139335 BC056342 BC068987
GenPept AAH56342 AAH68987 BAE23962
RNA Seq Atlas 237213

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca