Version 5.4
Mus musculus Gene: Slc17a5
Summary
InnateDB Gene IDBG-187019.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc17a5
Gene Name solute carrier family 17 (anion/sugar transporter), member 5
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000049624
Encoded Proteins
IDBP-187021
solute carrier family 17 (anion/sugar transporter), member 5
IDBP-400579
solute carrier family 17 (anion/sugar transporter), member 5
IDBP-400577
solute carrier family 17 (anion/sugar transporter), member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119899:
This gene encodes a membrane transporter that exports free sialic acids that have been cleaved off of cell surface lipids and proteins from lysosomes. Mutations in this gene cause sialic acid storage diseases, including infantile sialic acid storage disorder and and Salla disease, an adult form. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:78536488-78588041
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000052441 ENSMUSP00000056182
ENSMUST00000117645 ENSMUSP00000113003
ENSMUST00000119213 ENSMUSP00000113340
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015136 sialic acid transmembrane transporter activity
GO:0015293 symporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0006865 amino acid transport
GO:0015739 sialic acid transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000119899
View Gene Order
ENSBTAG00000044053
Not yet available
Pathways
NETPATH
REACTOME
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_248642
Synthesis of substrates in N-glycan biosythesis pathway
REACT_251788
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_262413
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_237472
Asparagine N-linked glycosylation pathway
REACT_251149
Organic anion transporters pathway
REACT_202500
Sialic acid metabolism pathway
KEGG
mmu04142
Lysosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19372
Organic anion transporters pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_22433
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_22161
Post-translational protein modification pathway
REACT_22387
Synthesis of substrates in N-glycan biosythesis pathway
REACT_200874
Sialic acid metabolism pathway
REACT_17015
Metabolism of proteins pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
hsa04142
Lysosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.394611 Mm.46932
RefSeq NM_001276452 NM_172773 XM_006511128 XM_006511129
OMIM
CCDS CCDS23364 CCDS72283
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca