Mus musculus Gene: Slc17a5

Summary
InnateDB Gene IDBG-187019.5
Last Modified 2012-02-14   [Report errors or provide feedback]
Gene Symbol Slc17a5
Gene Name solute carrier family 17 (anion/sugar transporter), member 5
Synonyms 4631416G20Rik; 4732491M05; AST; ISSD; NSD; SD; SIALIN; SIASD; SLD
Species Mus musculus
Ensembl Gene ENSMUSG00000049624
Encoded Proteins
IDBP-187021 solute carrier family 17 (anion/sugar transporter), member 5
IDBP-400579 solute carrier family 17 (anion/sugar transporter), member 5
IDBP-400577 solute carrier family 17 (anion/sugar transporter), member 5
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119899:
This gene encodes a membrane transporter that exports free sialic acids that have been cleaved off of cell surface lipids and proteins from lysosomes. Mutations in this gene cause sialic acid storage diseases, including infantile sialic acid storage disorder and and Salla disease, an adult form. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9: 78536488-78588041
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000052441  ENSMUSP00000056182
ENSMUST00000117645  ENSMUSP00000113003
ENSMUST00000119213  ENSMUSP00000113340
Interactions
Number of Interactions   This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
 
Predicted by orthology
Total 1 [view]
Gene Ontology
Accession GO Term
Molecular Function
GO:0015136 sialic acid transmembrane transporter activity
GO:0015293 symporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0015739 sialic acid transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0016021 integral to membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID Gene Order Method Confidence Comments
ENSG00000119899 Ortholuge SSD Ortholog Ortholog supports species divergence
ENSBTAG00000044053 Not yet available Ortholuge SSD Ortholog Ortholog supports species divergence
Pathways
NETPATH
REACTOME
REACT_98649 Organic anion transporters
KEGG
mmu04142  Lysosome
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19372 Organic anion transporters
KEGG
hsa04142  Lysosome
INOH
PID BIOCARTA
PID NCI
Organic_anion_transporters Organic anion transporters
Cross-References
SwissProt Q8BN82 
TrEMBL
UniProt Splice Variant
Entrez Gene 235504 
UniGene Mm.394611 Mm.46932
RefSeq NM_172773 
OMIM
CCDS CCDS23364 
HPRD
IMGT
MGI ID MGI:1924105 
MGI Symbol Slc17a5
EMBL AK029102 AK087395 AK169868 BC058785
GenPept AAH58785  BAC26298  BAC39859  BAE41423 
ImmGen Slc17a5 (murine) 
RNA Seq Atlas 235504