Mus musculus Gene: Slc17a5
Summary
InnateDB Gene IDBG-187019.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc17a5
Gene Name solute carrier family 17 (anion/sugar transporter), member 5
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000049624
Encoded Proteins
solute carrier family 17 (anion/sugar transporter), member 5
solute carrier family 17 (anion/sugar transporter), member 5
solute carrier family 17 (anion/sugar transporter), member 5
Protein Structure
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119899:
This gene encodes a membrane transporter that exports free sialic acids that have been cleaved off of cell surface lipids and proteins from lysosomes. Mutations in this gene cause sialic acid storage diseases, including infantile sialic acid storage disorder and and Salla disease, an adult form. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:78536488-78588041
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000052441 ENSMUSP00000056182
ENSMUST00000117645 ENSMUSP00000113003
ENSMUST00000119213 ENSMUSP00000113340
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015136 sialic acid transmembrane transporter activity
GO:0015293 symporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0006865 amino acid transport
GO:0015739 sialic acid transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
SLC-mediated transmembrane transport pathway
Synthesis of substrates in N-glycan biosythesis pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Transmembrane transport of small molecules pathway
Asparagine N-linked glycosylation pathway
Organic anion transporters pathway
Sialic acid metabolism pathway
KEGG
Lysosome pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
Post-translational protein modification pathway
Synthesis of substrates in N-glycan biosythesis pathway
Asparagine N-linked glycosylation pathway
Sialic acid metabolism pathway
Metabolism of proteins pathway
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Organic anion transporters pathway
SLC-mediated transmembrane transport pathway
KEGG
Lysosome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q8BN82
TrEMBL
UniProt Splice Variant
Entrez Gene 235504
UniGene Mm.394611 Mm.46932
RefSeq NM_001276452 NM_172773 XM_006511128 XM_006511129
OMIM
CCDS CCDS23364 CCDS72283
HPRD
IMGT
MGI ID MGI:1924105
MGI Symbol Slc17a5
EMBL AK029102 AK087395 AK169868 BC058785
GenPept AAH58785 BAC26298 BAC39859 BAE41423
ImmGen Slc17a5 (murine)
RNA Seq Atlas 235504