Mus musculus Gene: Ankle2
Summary
InnateDB Gene IDBG-189505.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ankle2
Gene Name ankyrin repeat and LEM domain containing 2
Synonyms 1110001J12Rik; AI661024; D5Ertd585e
Species Mus musculus
Ensembl Gene ENSMUSG00000029501
Encoded Proteins
ankyrin repeat and LEM domain containing 2
ankyrin repeat and LEM domain containing 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000176915:
This gene encodes a member of the LEM family of inner nuclear membrane proteins. The encoded protein functions as a mitotic regulator through postmitotic formation of the nuclear envelope. Mutations in this gene cause morphology defects in the nuclear envelope and BAF hyperphosphorylation. [provided by RefSeq, Mar 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:110231004-110256651
Strand Forward strand
Band F
Transcripts
ENSMUST00000031474 ENSMUSP00000031474
ENSMUST00000086674 ENSMUSP00000083878
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051721 protein phosphatase 2A binding
Biological Process
GO:0007067 mitotic nuclear division
GO:0007084 mitotic nuclear envelope reassembly
GO:0035307 positive regulation of protein dephosphorylation
GO:0042326 negative regulation of phosphorylation
Cellular Component
GO:0016020 membrane
GO:0030176 integral component of endoplasmic reticulum membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Cell Cycle, Mitotic pathway
Nuclear Envelope Reassembly pathway
Cell Cycle pathway
M Phase pathway
Mitotic Metaphase and Anaphase pathway
Initiation of Nuclear Envelope Reformation pathway
Mitotic Anaphase pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Initiation of Nuclear Envelope Reformation pathway
Cell Cycle pathway
M Phase pathway
Mitotic Anaphase pathway
Nuclear Envelope Reassembly pathway
Cell Cycle, Mitotic pathway
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.288442 Mm.410532
RefSeq NM_001253814 NM_027922
OMIM
CCDS CCDS57372
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas