Version 5.4
Mus musculus Gene: Satb1
Summary
InnateDB Gene IDBG-190608.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Satb1
Gene Name special AT-rich sequence binding protein 1
Synonyms 2610306G12Rik; AW413156
Species Mus musculus
Ensembl Gene ENSMUSG00000023927
Encoded Proteins
IDBP-540281
special AT-rich sequence binding protein 1
IDBP-537792
special AT-rich sequence binding protein 1
IDBP-533753
special AT-rich sequence binding protein 1
IDBP-533595
special AT-rich sequence binding protein 1
IDBP-540446
special AT-rich sequence binding protein 1
IDBP-534401
special AT-rich sequence binding protein 1
IDBP-533825
special AT-rich sequence binding protein 1
IDBP-532679
special AT-rich sequence binding protein 1
IDBP-625728
special AT-rich sequence binding protein 1
IDBP-715621
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182568:
This gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs through a unique nuclear architecture. The protein recruits chromatin-remodeling factors in order to regulate chromatin structure and gene expression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:51736187-51833290
Strand Reverse strand
Band C
Transcripts
ENSMUST00000144331 ENSMUSP00000116006
ENSMUST00000133574 ENSMUSP00000120536
ENSMUST00000152830 ENSMUSP00000119842
ENSMUST00000140979 ENSMUSP00000118839
ENSMUST00000129667 ENSMUSP00000116020
ENSMUST00000137697
ENSMUST00000140727
ENSMUST00000156051
ENSMUST00000129205 ENSMUSP00000123409
ENSMUST00000146414
ENSMUST00000124222 ENSMUSP00000116639
ENSMUST00000148559 ENSMUSP00000121224
ENSMUST00000169480 ENSMUSP00000128841
ENSMUST00000176669 ENSMUSP00000134957
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 24 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006325 chromatin organization
GO:0006338 chromatin remodeling
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008544 epidermis development
GO:0016571 histone methylation
GO:0042110 T cell activation
GO:0043367 CD4-positive, alpha-beta T cell differentiation
GO:0043374 CD8-positive, alpha-beta T cell differentiation
GO:0050798 activated T cell proliferation
GO:0060004 reflex
Cellular Component
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005720 nuclear heterochromatin
GO:0016363 nuclear matrix
GO:0016605 PML body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000182568
View Gene Order
ENSBTAG00000021158
Not yet available
Pathways
NETPATH
REACTOME
REACT_258521
Apoptosis pathway
REACT_224460
Apoptotic cleavage of cellular proteins pathway
REACT_207035
Apoptotic execution phase pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_107
Apoptotic cleavage of cellular proteins pathway
REACT_995
Apoptotic execution phase pathway
REACT_578
Apoptosis pathway
KEGG
INOH
PID NCI
caspase_pathway
Caspase Cascade in Apoptosis
Cross-References
SwissProt Q60611
TrEMBL D3YU76 D3YZD1 D3Z4F8 D3Z7K4 E9Q535 F8WHG2
UniProt Splice Variant
Entrez Gene 20230
UniGene Mm.311655 Mm.396994
RefSeq NM_001163632 NM_001163630 NM_001163631 NM_009122
OMIM
CCDS CCDS28876
HPRD
IMGT
MGI ID MGI:105084
MGI Symbol Satb1
EMBL AC131975 AC154796 AK088563 AK158518 BC011132 CH466559 CT010371 U05252
GenPept AAA17372 AAH11132 BAC40427 BAE34542 CAJ18578 EDL23652
RNA Seq Atlas 20230

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca