Version 5.4
Mus musculus Gene: Kdm5b
Summary
InnateDB Gene IDBG-193931.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kdm5b
Gene Name lysine (K)-specific demethylase 5B
Synonyms 2010009J12Rik; 2210016I17Rik; AW556288; D1Ertd202e; Jarid1b; mKIAA4034; PLU-1; Plu1; PUT1; Rb-Bp2; RBBP2H1A
Species Mus musculus
Ensembl Gene ENSMUSG00000042207
Encoded Proteins
IDBP-193933
lysine (K)-specific demethylase 5B
IDBP-256490
lysine (K)-specific demethylase 5B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117139:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:134560171-134635285
Strand Forward strand
Band E4
Transcripts
ENSMUST00000047714 ENSMUSP00000038138
ENSMUST00000112198 ENSMUSP00000107817
ENSMUST00000112197
ENSMUST00000133725
ENSMUST00000186128
ENSMUST00000191572
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 62 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 62 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0032453 histone demethylase activity (H3-K4 specific)
GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)
GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)
Biological Process
GO:0006351 transcription, DNA-templated
GO:0034720 histone H3-K4 demethylation
GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific
GO:0045892 negative regulation of transcription, DNA-templated
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005730 nucleolus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000117139
View Gene Order
ENSBTAG00000006175
Not yet available
Pathways
NETPATH
REACTOME
REACT_218274
Chromatin organization pathway
REACT_256030
HDMs demethylate histones pathway
REACT_202766
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_228178
HDMs demethylate histones pathway
REACT_172623
Chromatin organization pathway
REACT_172633
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_152895
OMIM
CCDS CCDS35716
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca