Version 5.4
Mus musculus Gene: Phactr4
Summary
InnateDB Gene IDBG-193951.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Phactr4
Gene Name phosphatase and actin regulator 4
Synonyms 3110001B12Rik; AI527228; AW495572; C330013F19Rik; mKIAA4120; N28169
Species Mus musculus
Ensembl Gene ENSMUSG00000066043
Encoded Proteins
IDBP-193953
phosphatase and actin regulator 4
IDBP-193955
phosphatase and actin regulator 4
IDBP-193957
phosphatase and actin regulator 4
IDBP-535364
phosphatase and actin regulator 4
IDBP-537972
phosphatase and actin regulator 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204138:
This gene encodes a member of the phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein phosphatase 1 (PP1) activity, and the homolog of this gene in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:132355923-132422489
Strand Reverse strand
Band D2.3
Transcripts
ENSMUST00000102568 ENSMUSP00000099628
ENSMUST00000084170 ENSMUSP00000081185
ENSMUST00000084249 ENSMUSP00000081270
ENSMUST00000127516
ENSMUST00000152271 ENSMUSP00000119767
ENSMUST00000136711 ENSMUSP00000122194
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0004864 protein phosphatase inhibitor activity
GO:0008157 protein phosphatase 1 binding
GO:0071862 protein phosphatase type 1 activator activity
Biological Process
GO:0001755 neural crest cell migration
GO:0001843 neural tube closure
GO:0007266 Rho protein signal transduction
GO:0030036 actin cytoskeleton organization
GO:0043085 positive regulation of catalytic activity
GO:0043086 negative regulation of catalytic activity
GO:0048484 enteric nervous system development
GO:0051726 regulation of cell cycle
GO:0061386 closure of optic fissure
GO:2001045 negative regulation of integrin-mediated signaling pathway
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0030027 lamellipodium
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000204138
View Gene Order
ENSBTAG00000002727
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.158361
RefSeq NM_001161797 NM_175306 XM_006538456 XM_006538457
OMIM
CCDS CCDS18724 CCDS51318
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca