Version 5.4
Bos taurus Gene: PHACTR4
Summary
InnateDB Gene IDBG-644882.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PHACTR4
Gene Name Phosphatase and actin regulator 4
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002727
Encoded Proteins
IDBP-697556
phosphatase and actin regulator 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204138:
This gene encodes a member of the phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein phosphatase 1 (PP1) activity, and the homolog of this gene in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:125507620-125558651
Strand Reverse strand
Band
Transcripts
ENSBTAT00000003535 ENSBTAP00000003535
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0008157 protein phosphatase 1 binding
GO:0071862 protein phosphatase type 1 activator activity
Biological Process
GO:0001755 neural crest cell migration
GO:0001843 neural tube closure
GO:0007266 Rho protein signal transduction
GO:0007275 multicellular organismal development
GO:0007399 nervous system development
GO:0030036 actin cytoskeleton organization
GO:0043085 positive regulation of catalytic activity
GO:0048484 enteric nervous system development
GO:0051726 regulation of cell cycle
GO:0061386 closure of optic fissure
GO:2001045 negative regulation of integrin-mediated signaling pathway
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0030027 lamellipodium
GO:0042995 cell projection
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000204138
View Gene Order
ENSMUSG00000066043
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.30560
RefSeq NM_001102007 XM_005203140 XM_005203141 XM_005203142 XM_005203143 XM_005203144
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca