Mus musculus Gene: Wasf2 | |||||||||||||||||||||||||
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Summary | |||||||||||||||||||||||||
InnateDB Gene | IDBG-194715.6 | ||||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||
Gene Symbol | Wasf2 | ||||||||||||||||||||||||
Gene Name | WAS protein family, member 2 | ||||||||||||||||||||||||
Synonyms | |||||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000028868 | ||||||||||||||||||||||||
Encoded Proteins |
WAS protein family, member 2
WAS protein family, member 2
WAS protein family, member 2
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Protein Structure | |||||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158195:
This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011] |
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Gene Information | |||||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||||
Genomic Location | Chromosome 4:133130505-133199756 | ||||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||||
Band | D2.3 | ||||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||||
REACTOME |
Innate Immune System pathway
Regulation of actin dynamics for phagocytic cup formation pathway
Signaling by VEGF pathway
Immune System pathway
VEGFA-VEGFR2 Pathway pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Signal Transduction pathway
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KEGG |
Regulation of actin cytoskeleton pathway
Adherens junction pathway
Fc gamma R-mediated phagocytosis pathway
Bacterial invasion of epithelial cells pathway
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INOH | |||||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||||
NETPATH |
TCR pathway
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REACTOME |
Regulation of actin dynamics for phagocytic cup formation pathway
Signaling by VEGF pathway
Innate Immune System pathway
Signal Transduction pathway
Immune System pathway
VEGFA-VEGFR2 Pathway pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
VEGFA-VEGFR2 Pathway pathway
Immune System pathway
Signal Transduction pathway
Regulation of actin dynamics for phagocytic cup formation pathway
Signaling by VEGF pathway
Innate Immune System pathway
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KEGG |
Regulation of actin cytoskeleton pathway
Adherens junction pathway
Fc gamma R-mediated phagocytosis pathway
Bacterial invasion of epithelial cells pathway
Shigellosis pathway
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INOH | |||||||||||||||||||||||||
PID NCI |
E-cadherin signaling in the nascent adherens junction
ErbB1 downstream signaling
RAC1 signaling pathway
PDGFR-beta signaling pathway
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Cross-References | |||||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||||
TrEMBL | B1AUN0 | ||||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||||
Entrez Gene | 242687 | ||||||||||||||||||||||||
UniGene | Mm.23566 Mm.416453 | ||||||||||||||||||||||||
RefSeq | NM_153423 XM_006538848 XM_006538849 XM_006538850 | ||||||||||||||||||||||||
OMIM | |||||||||||||||||||||||||
CCDS | CCDS18742 | ||||||||||||||||||||||||
HPRD | |||||||||||||||||||||||||
IMGT | |||||||||||||||||||||||||
MGI ID | MGI:1098641 | ||||||||||||||||||||||||
MGI Symbol | Wasf2 | ||||||||||||||||||||||||
EMBL | AL671858 | ||||||||||||||||||||||||
GenPept | |||||||||||||||||||||||||
RNA Seq Atlas | 242687 | ||||||||||||||||||||||||