Bos taurus Gene: WASF2 | |||||||||||||||||||||||||
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Summary | |||||||||||||||||||||||||
InnateDB Gene | IDBG-645020.3 | ||||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||
Gene Symbol | WASF2 | ||||||||||||||||||||||||
Gene Name | Wiskott-Aldrich syndrome protein family member 2 | ||||||||||||||||||||||||
Synonyms | |||||||||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||||||||
Ensembl Gene | ENSBTAG00000018374 | ||||||||||||||||||||||||
Encoded Proteins |
Wiskott-Aldrich syndrome protein family member 2
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Protein Structure | |||||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158195:
This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011] |
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Gene Information | |||||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||||
Genomic Location | Chromosome 2:126399312-126469335 | ||||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||||
Band | |||||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||||
REACTOME |
Fcgamma receptor (FCGR) dependent phagocytosis pathway
VEGFA-VEGFR2 Pathway pathway
Immune System pathway
Signal Transduction pathway
Regulation of actin dynamics for phagocytic cup formation pathway
Signaling by VEGF pathway
Innate Immune System pathway
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KEGG | |||||||||||||||||||||||||
INOH | |||||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||||
NETPATH |
TCR pathway
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REACTOME |
Regulation of actin dynamics for phagocytic cup formation pathway
Signaling by VEGF pathway
Innate Immune System pathway
Signal Transduction pathway
Immune System pathway
VEGFA-VEGFR2 Pathway pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Innate Immune System pathway
Regulation of actin dynamics for phagocytic cup formation pathway
Signaling by VEGF pathway
Immune System pathway
VEGFA-VEGFR2 Pathway pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Signal Transduction pathway
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KEGG |
Regulation of actin cytoskeleton pathway
Adherens junction pathway
Fc gamma R-mediated phagocytosis pathway
Bacterial invasion of epithelial cells pathway
Shigellosis pathway
Regulation of actin cytoskeleton pathway
Adherens junction pathway
Fc gamma R-mediated phagocytosis pathway
Bacterial invasion of epithelial cells pathway
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INOH | |||||||||||||||||||||||||
PID NCI |
E-cadherin signaling in the nascent adherens junction
ErbB1 downstream signaling
RAC1 signaling pathway
PDGFR-beta signaling pathway
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Cross-References | |||||||||||||||||||||||||
SwissProt | A2VDK6 | ||||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||||
Entrez Gene | 504482 | ||||||||||||||||||||||||
UniGene | Bt.38300 | ||||||||||||||||||||||||
RefSeq | NM_001081511 XM_005203087 XM_005203088 | ||||||||||||||||||||||||
HUGO | |||||||||||||||||||||||||
OMIM | |||||||||||||||||||||||||
CCDS | |||||||||||||||||||||||||
HPRD | |||||||||||||||||||||||||
IMGT | |||||||||||||||||||||||||
EMBL | BC133284 | ||||||||||||||||||||||||
GenPept | AAI33285 | ||||||||||||||||||||||||
RNA Seq Atlas | 504482 | ||||||||||||||||||||||||