Mus musculus Gene: Slc5a12
Summary
InnateDB Gene IDBG-195698.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc5a12
Gene Name solute carrier family 5 (sodium/glucose cotransporter), member 12
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000041644
Encoded Proteins
solute carrier family 5 (sodium/glucose cotransporter), member 12
solute carrier family 5 (sodium/glucose cotransporter), member 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148942:
Normal blood lactate is maintained at about 1.5 mM, and little filtered lactate is excreted in urine. Reabsorption of lactate is mediated by the low-affinity Na(+)-coupled lactate transporter SLC5A12 in the initial part of the proximal tubule and by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM 608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed 17692818]).[supplied by OMIM, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:110597298-110647779
Strand Forward strand
Band E3
Transcripts
ENSMUST00000045972 ENSMUSP00000047340
ENSMUST00000111026 ENSMUSP00000106655
ENSMUST00000138497
ENSMUST00000127822
ENSMUST00000146664
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0015293 symporter activity
Biological Process
GO:0006810 transport
GO:0006814 sodium ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q49B93
TrEMBL B9EJ03
UniProt Splice Variant
Entrez Gene 241612
UniGene Mm.277148
RefSeq NM_001003915 NM_001177624
OMIM
CCDS CCDS16512 CCDS50656
HPRD
IMGT
MGI ID MGI:2138890
MGI Symbol Slc5a12
EMBL AF529222 AK144004 AK165419 AL732495 AY964639 BC121791 BC141255 BX005257 CH466519
GenPept AAI21792 AAI41256 AAQ09530 AAY32930 BAE25658 BAE38174 CAM26858 CAM26859 CAM27818 CAM27819 EDL27797
RNA Seq Atlas 241612