Mus musculus Gene: Plcz1 | |||||||||||||||||
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Summary | |||||||||||||||||
InnateDB Gene | IDBG-195782.6 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | Plcz1 | ||||||||||||||||
Gene Name | phospholipase C, zeta 1 | ||||||||||||||||
Synonyms | |||||||||||||||||
Species | Mus musculus | ||||||||||||||||
Ensembl Gene | ENSMUSG00000030230 | ||||||||||||||||
Encoded Proteins |
phospholipase C, zeta 1
phospholipase C, zeta 1
phospholipase C, zeta 1
phospholipase C, zeta 1
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Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139151:
The protein encoded by this gene is a member of the phosphoinositide-specific phospholipase C family. Members in this family, classified into six isotypes that are tissue- and organ-specific, hydrolyze phosphatidylinositol 4,5-bisphosphate just before the phosphate group to yield diacylglycerol and inositol 1,4,5-trisphosphate. This protein localizes to the acrosome in spermatozoa and elicits Ca(2+) oscillations and egg activation during fertilization that leads to early embryonic development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |
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Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome 6:139989676-140041457 | ||||||||||||||||
Strand | Reverse strand | ||||||||||||||||
Band | G2 | ||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME |
Metabolism pathway
Inositol phosphate metabolism pathway
Synthesis of IP3 and IP4 in the cytosol pathway
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KEGG |
Calcium signaling pathway pathway
Phosphatidylinositol signaling system pathway
Inositol phosphate metabolism pathway
Oocyte meiosis pathway
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INOH | |||||||||||||||||
PID NCI | |||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME |
Synthesis of IP3 and IP4 in the cytosol pathway
Inositol phosphate metabolism pathway
Metabolism pathway
Synthesis of IP3 and IP4 in the cytosol pathway
Metabolism pathway
Inositol phosphate metabolism pathway
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KEGG |
Inositol phosphate metabolism pathway
Phosphatidylinositol signaling system pathway
Calcium signaling pathway pathway
Oocyte meiosis pathway
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INOH |
Inositol phosphate metabolism pathway
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PID NCI | |||||||||||||||||
Cross-References | |||||||||||||||||
SwissProt | |||||||||||||||||
TrEMBL | D6RCJ4 | ||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | 114875 | ||||||||||||||||
UniGene | Mm.50808 | ||||||||||||||||
RefSeq | NM_054066 XM_006506902 XM_006506903 | ||||||||||||||||
OMIM | |||||||||||||||||
CCDS | CCDS20671 | ||||||||||||||||
HPRD | |||||||||||||||||
IMGT | |||||||||||||||||
MGI ID | MGI:2150308 | ||||||||||||||||
MGI Symbol | Plcz1 | ||||||||||||||||
EMBL | AC158625 | ||||||||||||||||
GenPept | |||||||||||||||||
RNA Seq Atlas | 114875 | ||||||||||||||||