Bos taurus Gene: PLCZ1 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-639078.3 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | PLCZ1 | ||||||||||||||||||
Gene Name | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 | ||||||||||||||||||
Synonyms | PLCZ | ||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||
Ensembl Gene | ENSBTAG00000013202 | ||||||||||||||||||
Encoded Proteins |
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139151:
The protein encoded by this gene is a member of the phosphoinositide-specific phospholipase C family. Members in this family, classified into six isotypes that are tissue- and organ-specific, hydrolyze phosphatidylinositol 4,5-bisphosphate just before the phosphate group to yield diacylglycerol and inositol 1,4,5-trisphosphate. This protein localizes to the acrosome in spermatozoa and elicits Ca(2+) oscillations and egg activation during fertilization that leads to early embryonic development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 5:91771436-91820146 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | |||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
Synthesis of IP3 and IP4 in the cytosol pathway
Metabolism pathway
Inositol phosphate metabolism pathway
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KEGG | |||||||||||||||||||
INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
Synthesis of IP3 and IP4 in the cytosol pathway
Inositol phosphate metabolism pathway
Metabolism pathway
Metabolism pathway
Inositol phosphate metabolism pathway
Synthesis of IP3 and IP4 in the cytosol pathway
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KEGG |
Inositol phosphate metabolism pathway
Phosphatidylinositol signaling system pathway
Calcium signaling pathway pathway
Oocyte meiosis pathway
Calcium signaling pathway pathway
Phosphatidylinositol signaling system pathway
Inositol phosphate metabolism pathway
Oocyte meiosis pathway
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INOH |
Inositol phosphate metabolism pathway
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PID NCI | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | Q1RML2 | ||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 497026 | ||||||||||||||||||
UniGene | Bt.37187 | ||||||||||||||||||
RefSeq | NM_001011680 XM_005206975 XM_005206976 | ||||||||||||||||||
HUGO | |||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | |||||||||||||||||||
HPRD | |||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | AY646356 BC114836 | ||||||||||||||||||
GenPept | AAI14837 AAV54518 | ||||||||||||||||||
RNA Seq Atlas | 497026 | ||||||||||||||||||