Mus musculus Gene: Prg4 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-197710.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | Prg4 | ||||||||||||
Gene Name | proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein) | ||||||||||||
Synonyms | CACP; DOL54; JCAP; lubricin; MSF; SZP | ||||||||||||
Species | Mus musculus | ||||||||||||
Ensembl Gene | ENSMUSG00000006014 | ||||||||||||
Encoded Proteins |
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116690:
The protein encoded by this gene is a large proteoglycan specifically synthesized by chondrocytes located at the surface of articular cartilage, and also by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 1:150449412-150466165 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | G1 | ||||||||||||
Transcripts | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | |||||||||||||
UniGene | Mm.329131 | ||||||||||||
RefSeq | NM_001110146 NM_021400 XM_006529966 | ||||||||||||
OMIM | |||||||||||||
CCDS | CCDS48391 CCDS48392 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
MGI ID | |||||||||||||
MGI Symbol | |||||||||||||
EMBL | |||||||||||||
GenPept | |||||||||||||
RNA Seq Atlas | |||||||||||||