Version 5.4
Mus musculus Gene: Ppip5k1
Summary
InnateDB Gene IDBG-202057.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ppip5k1
Gene Name diphosphoinositol pentakisphosphate kinase 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000033526
Encoded Proteins
IDBP-202059
diphosphoinositol pentakisphosphate kinase 1
IDBP-259851
diphosphoinositol pentakisphosphate kinase 1
IDBP-259853
diphosphoinositol pentakisphosphate kinase 1
IDBP-259855
diphosphoinositol pentakisphosphate kinase 1
IDBP-259857
diphosphoinositol pentakisphosphate kinase 1
IDBP-534872
diphosphoinositol pentakisphosphate kinase 1
IDBP-538639
diphosphoinositol pentakisphosphate kinase 1
IDBP-533470
diphosphoinositol pentakisphosphate kinase 1
IDBP-532662
diphosphoinositol pentakisphosphate kinase 1
IDBP-541261
diphosphoinositol pentakisphosphate kinase 1
IDBP-534789
diphosphoinositol pentakisphosphate kinase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168781:
This gene encodes a dual functional inositol kinase. The encoded enzyme converts inositol hexakisphosphate to diphosphoinositol pentakisphosphate and diphosphoinositol pentakisphosphate to bis-diphosphoinositol tetrakisphosphate. This protein may be important for intracellular signaling pathways. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 15.[provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:121310561-121355396
Strand Reverse strand
Band E5
Transcripts
ENSMUST00000052029 ENSMUSP00000057632
ENSMUST00000110628 ENSMUSP00000106258
ENSMUST00000110627 ENSMUSP00000106257
ENSMUST00000110626 ENSMUSP00000106256
ENSMUST00000110625 ENSMUSP00000106255
ENSMUST00000132114 ENSMUSP00000117948
ENSMUST00000132613 ENSMUSP00000119577
ENSMUST00000127255 ENSMUSP00000118597
ENSMUST00000155568 ENSMUSP00000116335
ENSMUST00000132617
ENSMUST00000134644
ENSMUST00000142364
ENSMUST00000150081
ENSMUST00000137087 ENSMUSP00000115051
ENSMUST00000129276
ENSMUST00000131661
ENSMUST00000140764
ENSMUST00000134796 ENSMUSP00000122603
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity
GO:0000832 inositol hexakisphosphate 5-kinase activity
GO:0003993 acid phosphatase activity
GO:0005524 ATP binding
GO:0033857 diphosphoinositol-pentakisphosphate kinase activity
GO:0052723 inositol hexakisphosphate 1-kinase activity
GO:0052724 inositol hexakisphosphate 3-kinase activity
Biological Process
GO:0006020 inositol metabolic process
GO:0016310 phosphorylation
GO:0016311 dephosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000168781
View Gene Order
ENSBTAG00000014005
Not yet available
Pathways
NETPATH
REACTOME
REACT_188937
Metabolism pathway
REACT_196482
Synthesis of pyrophosphates in the cytosol pathway
REACT_196476
Inositol phosphate metabolism pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150188
Synthesis of pyrophosphates in the cytosol pathway
REACT_150154
Inositol phosphate metabolism pathway
REACT_111217
Metabolism pathway
REACT_218731
Synthesis of pyrophosphates in the cytosol pathway
REACT_219139
Metabolism pathway
REACT_211106
Inositol phosphate metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 327655
UniGene Mm.386076
RefSeq NM_178795 XM_006499741
OMIM
CCDS CCDS16639
HPRD
IMGT
MGI ID MGI:2443281
MGI Symbol Ppip5k1
EMBL
GenPept
RNA Seq Atlas 327655

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca