Version 5.4
Mus musculus Gene: Bpi
Summary
InnateDB Gene IDBG-211473.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bpi
Gene Name bactericidal permeablility increasing protein
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000052922
Encoded Proteins
IDBP-211475
bactericidal permeablility increasing protein
IDBP-262255
bactericidal permeablility increasing protein
IDBP-262257
bactericidal permeablility increasing protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101425:
This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:158258094-158284531
Strand Forward strand
Band H1
Transcripts
ENSMUST00000065039 ENSMUSP00000067837
ENSMUST00000109500 ENSMUSP00000105126
ENSMUST00000109499 ENSMUSP00000105125
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001530 lipopolysaccharide binding
GO:0008289 lipid binding
Biological Process
GO:0006955 immune response
GO:0032715 negative regulation of interleukin-6 production
GO:0032717 negative regulation of interleukin-8 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0042742 defense response to bacterium
GO:0043031 negative regulation of macrophage activation
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000101425
View Gene Order
Cross-References
SwissProt Q67E05
TrEMBL
UniProt Splice Variant
Entrez Gene 329547
UniGene Mm.260883
RefSeq NM_177850 XM_006499789
OMIM
CCDS CCDS16987
HPRD
IMGT
MGI ID MGI:3045315
MGI Symbol Bpi
EMBL AK033770 AL663063 AY363993 AY648037 AY853179 BC118049 BC118504
GenPept AAI18050 AAI18505 AAR13289 AAV65841 AAW50819 BAC28468 CAM23524 CAM23525 CAM23526
RNA Seq Atlas 329547

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca