Version 5.4
Mus musculus Gene: G6pc3
Summary
InnateDB Gene IDBG-212501.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol G6pc3
Gene Name glucose 6 phosphatase, catalytic, 3
Synonyms 0710001K01Rik; AU019276; AU045429; AV128920; AW545836; UGRP
Species Mus musculus
Ensembl Gene ENSMUSG00000034793
Encoded Proteins
IDBP-212503
glucose 6 phosphatase, catalytic, 3
IDBP-212505
glucose 6 phosphatase, catalytic, 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141349:
This gene encodes the catalytic subunit of glucose-6-phosphatase (G6Pase). G6Pase is located in the endoplasmic reticulum (ER) and catalyzes the hydrolysis of glucose-6-phosphate to glucose and phosphate in the last step of the gluconeogenic and glycogenolytic pathways. Mutations in this gene result in autosomal recessive severe congenital neutropenia. Multiple transcript variants have been found for this gene, only one of which is expected to express a protein.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:102189620-102194081
Strand Forward strand
Band D
Transcripts
ENSMUST00000070334 ENSMUSP00000064276
ENSMUST00000078975 ENSMUSP00000077995
ENSMUST00000131382
ENSMUST00000139995
ENSMUST00000124594
ENSMUST00000145490
ENSMUST00000153178
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004346 glucose-6-phosphatase activity
Biological Process
GO:0006094 gluconeogenesis
GO:0006796 phosphate-containing compound metabolic process
GO:0015760 glucose-6-phosphate transport
GO:0016311 dephosphorylation
GO:0051156 glucose 6-phosphate metabolic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000141349
View Gene Order
ENSBTAG00000016253
Not yet available
Pathways
NETPATH
REACTOME
REACT_189085
Disease pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_188937
Metabolism pathway
REACT_253543
Glucose transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_240125
Hexose transport pathway
REACT_203949
Glycogen storage diseases pathway
REACT_203841
Myoclonic epilepsy of Lafora pathway
REACT_248571
Metabolism of carbohydrates pathway
KEGG
mmu04910
Insulin signaling pathway pathway
mmu00010
Glycolysis / Gluconeogenesis pathway
mmu00500
Starch and sucrose metabolism pathway
mmu00052
Galactose metabolism pathway
mmu04920
Adipocytokine signaling pathway pathway
mmu04973
Carbohydrate digestion and absorption pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_212
Glucose transport pathway
REACT_9441
Hexose transport pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_200783
Myoclonic epilepsy of Lafora pathway
REACT_474
Metabolism of carbohydrates pathway
REACT_111217
Metabolism pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_116125
Disease pathway
REACT_200833
Glycogen storage diseases pathway
REACT_221274
Metabolism of carbohydrates pathway
REACT_222460
SLC-mediated transmembrane transport pathway
REACT_203892
Hexose transport pathway
REACT_219973
Myoclonic epilepsy of Lafora pathway
REACT_223103
Transmembrane transport of small molecules pathway
REACT_204270
Glucose transport pathway
REACT_211129
Glycogen storage diseases pathway
REACT_219139
Metabolism pathway
REACT_207087
Disease pathway
KEGG
hsa00052
Galactose metabolism pathway
hsa00010
Glycolysis / Gluconeogenesis pathway
hsa04910
Insulin signaling pathway pathway
hsa00500
Starch and sucrose metabolism pathway
hsa04920
Adipocytokine signaling pathway pathway
hsa04973
Carbohydrate digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.22385
RefSeq NM_175935
OMIM
CCDS CCDS25491
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca