Mus musculus Gene: Ntsr1
Summary
InnateDB Gene IDBG-213841.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ntsr1
Gene Name neurotensin receptor 1
Synonyms NT-1R; NTR-1; NTR1
Species Mus musculus
Ensembl Gene ENSMUSG00000027568
Encoded Proteins
neurotensin receptor 1
neurotensin receptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101188:
Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:180499976-180544980
Strand Forward strand
Band H4
Transcripts
ENSMUST00000029084 ENSMUSP00000029084
ENSMUST00000170448 ENSMUSP00000127548
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0005515 protein binding
GO:0008188 neuropeptide receptor activity
GO:0016492 G-protein coupled neurotensin receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0008344 adult locomotory behavior
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
GPCR ligand binding pathway
Peptide ligand-binding receptors pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
KEGG
Calcium signaling pathway pathway
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Peptide ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
KEGG
Neuroactive ligand-receptor interaction pathway
Calcium signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt O88319
TrEMBL A2ACT4 Q9QZQ2
UniProt Splice Variant
Entrez Gene 18216
UniGene Mm.301712
RefSeq NM_018766
OMIM
CCDS CCDS17177
HPRD
IMGT
MGI ID MGI:97386
MGI Symbol Ntsr1
EMBL AB017027 AF172326 BC138630 BC138633 CH466626
GenPept AAD51806 AAI38631 AAI38634 BAA33013 EDL07336
RNA Seq Atlas 18216