Version 5.4
Mus musculus Gene: Ict1
Summary
InnateDB Gene IDBG-214293.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ict1
Gene Name immature colon carcinoma transcript 1
Synonyms 1110001A02Rik; 1110002E03Rik; MRP-L58
Species Mus musculus
Ensembl Gene ENSMUSG00000018858
Encoded Proteins
IDBP-214297
immature colon carcinoma transcript 1
IDBP-268557
immature colon carcinoma transcript 1
IDBP-542851
immature colon carcinoma transcript 1
IDBP-542853
immature colon carcinoma transcript 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167862:
The adult colon epithelium contains 3 differentiated cell types that arise from a multipotent stem cell. Deviation from the normal maturation pathway by neoplastic transformation is thought to initiate in stem cells or their early descendants. One potential marker is ICT1 whose mRNA and protein were more highly expressed in undifferentiated than in differentiated cells. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:115403752-115412674
Strand Forward strand
Band E2
Transcripts
ENSMUST00000021079
ENSMUST00000103036 ENSMUSP00000099325
ENSMUST00000106539 ENSMUSP00000102149
ENSMUST00000153983 ENSMUSP00000116746
ENSMUST00000128632
ENSMUST00000122946 ENSMUSP00000116245
ENSMUST00000133192
ENSMUST00000135619
ENSMUST00000155134
ENSMUST00000134386
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 234 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 234 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003747 translation release factor activity
GO:0004045 aminoacyl-tRNA hydrolase activity
GO:0016150 translation release factor activity, codon nonspecific
Biological Process
GO:0006415 translational termination
GO:0070126 mitochondrial translational termination
Cellular Component
GO:0005739 mitochondrion
GO:0005762 mitochondrial large ribosomal subunit
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000167862
View Gene Order
ENSBTAG00000003303
Not yet available
Pathways
NETPATH
REACTOME
REACT_268789
Mitochondrial translation pathway
REACT_224594
Organelle biogenesis and maintenance pathway
REACT_270125
Mitochondrial translation elongation pathway
REACT_271096
Mitochondrial translation initiation pathway
REACT_270158
Mitochondrial translation termination pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_200751
Organelle biogenesis and maintenance pathway
REACT_267673
Mitochondrial translation pathway
REACT_267680
Mitochondrial translation initiation pathway
REACT_267602
Mitochondrial translation termination pathway
REACT_267677
Mitochondrial translation elongation pathway
REACT_270797
Mitochondrial translation initiation pathway
REACT_271447
Mitochondrial translation elongation pathway
REACT_270450
Mitochondrial translation pathway
REACT_270960
Mitochondrial translation termination pathway
REACT_219259
Organelle biogenesis and maintenance pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.271062
RefSeq NM_026729 XM_006534064
OMIM
CCDS CCDS25632
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca