Version 5.4
Homo sapiens Gene: SCAMP5
Summary
InnateDB Gene IDBG-22989.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCAMP5
Gene Name secretory carrier membrane protein 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000198794
Encoded Proteins
IDBP-22991
secretory carrier membrane protein 5
IDBP-377949
secretory carrier membrane protein 5
IDBP-744498
IDBP-746127
IDBP-744650
IDBP-747025
IDBP-746426
IDBP-746902
IDBP-746287
IDBP-746898
IDBP-744541
IDBP-745872
IDBP-745079
IDBP-746400
IDBP-745957
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 19234194
Promotes calcium-regulated exocytosis of signal peptide-containing cytokine secretion (CCL5 but not IL-1beta) in human monocytes and mouse macrophages
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:74957219-75021496
Strand Forward strand
Band q24.2
Transcripts
ENST00000361900 ENSP00000355387
ENST00000425597 ENSP00000406547
ENST00000564779 ENSP00000455039
ENST00000564141
ENST00000568119 ENSP00000457444
ENST00000565923
ENST00000562212 ENSP00000455313
ENST00000568081 ENSP00000454602
ENST00000568423 ENSP00000457520
ENST00000568018 ENSP00000456991
ENST00000567535
ENST00000567920 ENSP00000454860
ENST00000566872 ENSP00000454766
ENST00000565989 ENSP00000457121
ENST00000564491 ENSP00000458072
ENST00000562327 ENSP00000456505
ENST00000567529 ENSP00000455203
ENST00000562765 ENSP00000455598
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006887 exocytosis
GO:0015031 protein transport
GO:0034976 response to endoplasmic reticulum stress
GO:0045087 innate immune response (InnateDB)
GO:0045806 negative regulation of endocytosis
GO:0045956 positive regulation of calcium ion-dependent exocytosis
GO:0050715 positive regulation of cytokine secretion
Cellular Component
GO:0000139 Golgi membrane
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
GO:0031201 SNARE complex
GO:0032588 trans-Golgi network membrane
GO:0055038 recycling endosome membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040722
View Gene Order
ENSBTAG00000021318
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.627551
RefSeq NM_001178111 NM_001178112 NM_138967 XM_006720420 XM_006720421
HUGO
OMIM
CCDS CCDS45306
HPRD 18020
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca