Mus musculus Gene: Gp6 | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-264209.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | Gp6 | ||||||
Gene Name | glycoprotein 6 (platelet) | ||||||
Synonyms | |||||||
Species | Mus musculus | ||||||
Ensembl Gene | ENSMUSG00000078810 | ||||||
Encoded Proteins |
glycoprotein 6 (platelet)
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000088053:
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 7:4368713-4397744 | ||||||
Strand | Reverse strand | ||||||
Band | A1 | ||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||
NETPATH | |||||||
REACTOME |
Hemostasis pathway
Cell surface interactions at the vascular wall pathway
Platelet activation, signaling and aggregation pathway
Platelet Adhesion to exposed collagen pathway
GPVI-mediated activation cascade pathway
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KEGG |
ECM-receptor interaction pathway
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INOH | |||||||
PID NCI | |||||||
Pathway Predictions based on Human Orthology Data | |||||||
NETPATH | |||||||
REACTOME |
Cell surface interactions at the vascular wall pathway
Platelet Adhesion to exposed collagen pathway
GPVI-mediated activation cascade pathway
Platelet activation, signaling and aggregation pathway
Hemostasis pathway
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KEGG |
ECM-receptor interaction pathway
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INOH | |||||||
PID NCI | |||||||
Cross-References | |||||||
SwissProt | P0C191 | ||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 243816 | ||||||
UniGene | Mm.248662 | ||||||
RefSeq | NM_001163014 | ||||||
OMIM | |||||||
CCDS | CCDS51972 | ||||||
HPRD | |||||||
IMGT | |||||||
MGI ID | MGI:1889810 | ||||||
MGI Symbol | Gp6 | ||||||
EMBL | AC137969 | ||||||
GenPept | |||||||
RNA Seq Atlas | 243816 | ||||||