InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: GNAO1

Summary

InnateDB Gene

IDBG-31702.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GNAO1

Gene Name

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

Synonyms

EIEE17; G-ALPHA-o; GNAO

Species

Homo sapiens

Ensembl Gene

ENSG00000087258

Encoded Proteins

IDBP-31704

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

IDBP-31706

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

IDBP-754048

IDBP-749930

IDBP-750630

IDBP-748701

IDBP-810437

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 16:56191390-56357444

Strand

Forward strand

Band

q13

Transcripts

ENST00000262494	ENSP00000262494
ENST00000262493	ENSP00000262493
ENST00000563440	ENSP00000455774
ENST00000563661
ENST00000562316	ENSP00000457238
ENST00000564727	ENSP00000454971
ENST00000565363	ENSP00000454728
ENST00000564798
ENST00000569295
ENST00000568375
ENST00000570235	ENSP00000477740

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	22 [view]
Protein-Protein	22 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0004871	signal transducer activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0019001	guanyl nucleotide binding
GO:0031683	G-protein beta/gamma-subunit complex binding
GO:0031821	G-protein coupled serotonin receptor binding
GO:0031852	mu-type opioid receptor binding
GO:0032403	protein complex binding
GO:0032794	GTPase activating protein binding
GO:0046872	metal ion binding
GO:0051430	corticotropin-releasing hormone receptor 1 binding

Biological Process

GO:0006184	GTP catabolic process
GO:0006936	muscle contraction
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007212	dopamine receptor signaling pathway
GO:0007568	aging
GO:0007626	locomotory behavior
GO:0008016	regulation of heart contraction
GO:0009987	cellular process
GO:0010243	response to organonitrogen compound
GO:0014070	response to organic cyclic compound
GO:0030900	forebrain development
GO:0031175	neuron projection development
GO:0034097	response to cytokine
GO:0042493	response to drug
GO:0042542	response to hydrogen peroxide
GO:0043278	response to morphine
GO:0043547	positive regulation of GTPase activity
GO:0051926	negative regulation of calcium ion transport

Cellular Component

GO:0005622	intracellular
GO:0005834	heterotrimeric G-protein complex
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0043005	neuron projection
GO:0043234	protein complex