InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Gnao1

Summary

InnateDB Gene

IDBG-181138.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gnao1

Gene Name

guanine nucleotide binding protein, alpha O

Synonyms

alphaO; AW050213; Galphao; Gnao

Species

Mus musculus

Ensembl Gene

ENSMUSG00000031748

Encoded Proteins

IDBP-181140

guanine nucleotide binding protein, alpha O

IDBP-540529

guanine nucleotide binding protein, alpha O

IDBP-541205

guanine nucleotide binding protein, alpha O

IDBP-533048

guanine nucleotide binding protein, alpha O

IDBP-534238

guanine nucleotide binding protein, alpha O

IDBP-538807

guanine nucleotide binding protein, alpha O

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000087258:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:93809966-93969388

Strand

Forward strand

Band

Transcripts

ENSMUST00000034198	ENSMUSP00000034198
ENSMUST00000137202	ENSMUSP00000119220
ENSMUST00000125695
ENSMUST00000125716	ENSMUSP00000114144
ENSMUST00000138659
ENSMUST00000127900	ENSMUSP00000116826
ENSMUST00000130974
ENSMUST00000149530	ENSMUSP00000115007
ENSMUST00000142466	ENSMUSP00000118463
ENSMUST00000144451
ENSMUST00000155245

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	17 [view]
Protein-Protein	16 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0004871	signal transducer activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0019001	guanyl nucleotide binding
GO:0031683	G-protein beta/gamma-subunit complex binding
GO:0031821	G-protein coupled serotonin receptor binding
GO:0031852	mu-type opioid receptor binding
GO:0032403	protein complex binding
GO:0032794	GTPase activating protein binding
GO:0046872	metal ion binding
GO:0051430	corticotropin-releasing hormone receptor 1 binding

Biological Process

GO:0006184	GTP catabolic process
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007212	dopamine receptor signaling pathway
GO:0007568	aging
GO:0007626	locomotory behavior
GO:0008016	regulation of heart contraction
GO:0009987	cellular process
GO:0010243	response to organonitrogen compound
GO:0014070	response to organic cyclic compound
GO:0030900	forebrain development
GO:0031175	neuron projection development
GO:0034097	response to cytokine
GO:0042493	response to drug
GO:0042542	response to hydrogen peroxide
GO:0043278	response to morphine
GO:0043547	positive regulation of GTPase activity
GO:0051926	negative regulation of calcium ion transport

Cellular Component

GO:0005622	intracellular
GO:0005834	heterotrimeric G-protein complex
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
GO:0043005	neuron projection
GO:0043234	protein complex