Version 5.4
Homo sapiens Gene: ALKBH5
Summary
InnateDB Gene IDBG-33623.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALKBH5
Gene Name alkB, alkylation repair homolog 5 (E. coli)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000091542
Encoded Proteins
IDBP-231414
alkB, alkylation repair homolog 5 (E. coli)
IDBP-760935
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:18183078-18209954
Strand Forward strand
Band p11.2
Transcripts
ENST00000399138 ENSP00000382091
ENST00000490106
ENST00000541285 ENSP00000468116
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0035515 oxidative RNA demethylase activity
GO:0044822 poly(A) RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0001666 response to hypoxia
GO:0006397 mRNA processing
GO:0006406 mRNA export from nucleus
GO:0007283 spermatogenesis
GO:0030154 cell differentiation
GO:0035553 oxidative single-stranded RNA demethylation
Cellular Component
GO:0005634 nucleus
GO:0016607 nuclear speck
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042650
View Gene Order
ENSBTAG00000025046
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.462392 Hs.743779
RefSeq NM_017758
HUGO
OMIM
CCDS CCDS42272
HPRD 08621
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca