Bos taurus Gene: FBXO8 | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-629323.3 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | FBXO8 | ||||||||
Gene Name | F-box only protein 8 | ||||||||
Synonyms | |||||||||
Species | Bos taurus | ||||||||
Ensembl Gene | ENSBTAG00000006715 | ||||||||
Encoded Proteins |
F-box only protein 8
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Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164117:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 8:6410067-6449539 | ||||||||
Strand | Reverse strand | ||||||||
Band | |||||||||
Transcripts |
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Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||
NETPATH | |||||||||
REACTOME | |||||||||
KEGG | |||||||||
INOH | |||||||||
PID NCI |
Arf6 signaling events
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Cross-References | |||||||||
SwissProt | Q5E9G6 | ||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | 538528 | ||||||||
UniGene | Bt.37057 | ||||||||
RefSeq | NM_001015667 XM_005209814 | ||||||||
HUGO | |||||||||
OMIM | |||||||||
CCDS | |||||||||
HPRD | |||||||||
IMGT | |||||||||
EMBL | BC103444 BT020782 BT020954 | ||||||||
GenPept | AAI03445 AAX08799 AAX08971 | ||||||||
RNA Seq Atlas | 538528 | ||||||||