Bos taurus Gene: NPPA | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-632583.3 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | NPPA | ||||||||||||
Gene Name | Natriuretic peptides A Atrial natriuretic factor | ||||||||||||
Synonyms | |||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Gene | ENSBTAG00000006709 | ||||||||||||
Encoded Proteins |
Natriuretic peptides AAtrial natriuretic factor
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175206:
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq, Sep 2009] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 16:42712044-42713502 | ||||||||||||
Strand | Forward strand | ||||||||||||
Band | |||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
YAP1- and WWTR1 (TAZ)-stimulated gene expression pathway
Generic Transcription Pathway pathway
Amyloids pathway
Gene Expression pathway
Disease pathway
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KEGG | |||||||||||||
INOH | |||||||||||||
PID NCI | |||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Amyloids pathway
YAP1- and WWTR1 (TAZ)-stimulated gene expression pathway
Generic Transcription Pathway pathway
Gene Expression pathway
Disease pathway
Disease pathway
Amyloids pathway
Gene Expression pathway
YAP1- and WWTR1 (TAZ)-stimulated gene expression pathway
Generic Transcription Pathway pathway
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KEGG | |||||||||||||
INOH |
GPCR signaling pathway
GPCR signaling pathway
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PID NCI |
AP-1 transcription factor network
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Cross-References | |||||||||||||
SwissProt | P07501 | ||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 281355 | ||||||||||||
UniGene | Bt.29967 | ||||||||||||
RefSeq | NM_174124 | ||||||||||||
HUGO | |||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | BC149029 M13145 | ||||||||||||
GenPept | AAA30375 AAI49030 | ||||||||||||
RNA Seq Atlas | 281355 | ||||||||||||