InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SRSF7

Summary

InnateDB Gene

IDBG-632653.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SRSF7

Gene Name

Serine/arginine-rich splicing factor 7

Synonyms

SFRS7

Species

Bos taurus

Ensembl Gene

ENSBTAG00000014891

Encoded Proteins

IDBP-684284

Serine/arginine-rich splicing factor 7

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115875:
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:21105343-21110797

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000033124

ENSBTAP00000033048

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 69 interaction(s) predicted by orthology.

Predicted by orthology
Total	69 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0044822	poly(A) RNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006397	mRNA processing
GO:0006810	transport
GO:0008380	RNA splicing
GO:0048025	negative regulation of mRNA splicing, via spliceosome
GO:0051028	mRNA transport