Version 5.4
Bos taurus Gene: EXOSC10
Summary
InnateDB Gene IDBG-632920.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EXOSC10
Gene Name exosome component 10
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002590
Encoded Proteins
IDBP-684690
exosome component 10
IDBP-684707
exosome component 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171824:
Gene Information
Type Protein coding
Genomic Location Chromosome 16:43403640-43426116
Strand Forward strand
Band
Transcripts
ENSBTAT00000057296 ENSBTAP00000048640
ENSBTAT00000003354 ENSBTAP00000003354
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 56 interaction(s) predicted by orthology.
Predicted by orthology
Total 56 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003824 catalytic activity
GO:0004532 exoribonuclease activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000460 maturation of 5.8S rRNA
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006396 RNA processing
GO:0009048 dosage compensation by inactivation of X chromosome
GO:0044237 cellular metabolic process
GO:0071028 nuclear mRNA surveillance
GO:0071034 CUT catabolic process
GO:0071035 nuclear polyadenylation-dependent rRNA catabolic process
GO:0071044 histone mRNA catabolic process
GO:0071048 nuclear retention of unspliced pre-mRNA at the site of transcription
GO:0090305 nucleic acid phosphodiester bond hydrolysis
GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic
Cellular Component
GO:0000176 nuclear exosome (RNase complex)
GO:0000178 exosome (RNase complex)
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0035327 transcriptionally active chromatin
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000171824
View Gene Order
ENSMUSG00000017264
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03018
RNA degradation pathway
mmu03018
RNA degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A7E323 E1BMZ5
UniProt Splice Variant
Entrez Gene 535340
UniGene Bt.59475
RefSeq NM_001102186 XM_005216968 XM_005216969
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151674 DAAA02042967
GenPept AAI51675
RNA Seq Atlas 535340

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca