Bos taurus Gene: ADSSL1
Summary
InnateDB Gene IDBG-635746.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADSSL1
Gene Name Adenylosuccinate synthetase isozyme 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000017616
Encoded Proteins
Adenylosuccinate synthetase isozyme 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185100:
ADSSL1 is a muscle isozyme of adenylosuccinate synthase (EC 6.3.4.4), which catalyzes the initial reaction in the conversion of inosine monophosphate (IMP) to adenosine monophosphate (AMP) (Sun et al., 2005 [PubMed 15786719]).[supplied by OMIM, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:70845971-70861972
Strand Forward strand
Band
Transcripts
ENSBTAT00000044296 ENSBTAP00000041803
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0004019 adenylosuccinate synthase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006163 purine nucleotide metabolic process
GO:0006164 purine nucleotide biosynthetic process
GO:0006167 AMP biosynthetic process
GO:0044208 'de novo' AMP biosynthetic process
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Metabolism of nucleotides pathway
Purine metabolism pathway
Metabolism pathway
Purine ribonucleoside monophosphate biosynthesis pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Purine ribonucleoside monophosphate biosynthesis pathway
Metabolism of nucleotides pathway
Purine metabolism pathway
Metabolism pathway
Purine metabolism pathway
Metabolism pathway
Purine ribonucleoside monophosphate biosynthesis pathway
Metabolism of nucleotides pathway
KEGG
Purine metabolism pathway
Alanine, aspartate and glutamate metabolism pathway
Purine metabolism pathway
Alanine, aspartate and glutamate metabolism pathway
INOH
Purine nucleotides nucleosides metabolism pathway
Alanine Aspartate Asparagine metabolism pathway
PID NCI
Cross-References
SwissProt A5PJR4
TrEMBL
UniProt Splice Variant
Entrez Gene 784089
UniGene Bt.16782
RefSeq NM_001099192 XM_005196345 XM_005196346 XM_005196348 XM_005196349 XM_005196350 XM_005222254 XM_005222256 XM_005222257 XM_005222258
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC142211
GenPept AAI42212
RNA Seq Atlas 101908640 784089