Bos taurus Gene: SEMA4D
Summary
InnateDB Gene IDBG-637043.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEMA4D
Gene Name semaphorin-4D precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001941
Encoded Proteins
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187764:
Gene Information
Type Protein coding
Genomic Location Chromosome 8:90136712-90262973
Strand Forward strand
Band
Transcripts
ENSBTAT00000002525 ENSBTAP00000002525
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0004888 transmembrane signaling receptor activity
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0030215 semaphorin receptor binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001934 positive regulation of protein phosphorylation
GO:0007162 negative regulation of cell adhesion
GO:0007275 multicellular organismal development
GO:0008360 regulation of cell shape
GO:0010693 negative regulation of alkaline phosphatase activity
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0030335 positive regulation of cell migration
GO:0031344 regulation of cell projection organization
GO:0032321 positive regulation of Rho GTPase activity
GO:0043931 ossification involved in bone maturation
GO:0045668 negative regulation of osteoblast differentiation
GO:0048672 positive regulation of collateral sprouting
GO:0048814 regulation of dendrite morphogenesis
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation
GO:0050772 positive regulation of axonogenesis
GO:0070486 leukocyte aggregation
GO:0071526 semaphorin-plexin signaling pathway
GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis
Cellular Component
GO:0005615 extracellular space
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Sema4D mediated inhibition of cell attachment and migration pathway
Sema4D induced cell migration and growth-cone collapse pathway
Sema4D in semaphorin signaling pathway
Other semaphorin interactions pathway
Developmental Biology pathway
Semaphorin interactions pathway
Axon guidance pathway
Sema4D induced cell migration and growth-cone collapse pathway
Axon guidance pathway
Sema4D in semaphorin signaling pathway
Developmental Biology pathway
Semaphorin interactions pathway
Sema4D mediated inhibition of cell attachment and migration pathway
Other semaphorin interactions pathway
KEGG
Axon guidance pathway
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.103001
RefSeq NM_001098160
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas