InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: XRN2

Summary

InnateDB Gene

IDBG-639077.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

XRN2

Gene Name

5'-3' exoribonuclease 2

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000011304

Encoded Proteins

IDBP-691204

5'-3' exoribonuclease 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000088930:
This gene shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for this gene; however, their full-length nature is not known. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:40962751-41025285

Strand

Forward strand

Band

Transcripts

ENSBTAT00000015019

ENSBTAP00000015019

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.

Predicted by orthology
Total	32 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0004527	exonuclease activity
GO:0004534	5'-3' exoribonuclease activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0008409	5'-3' exonuclease activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000738	DNA catabolic process, exonucleolytic
GO:0006139	nucleobase-containing compound metabolic process
GO:0007283	spermatogenesis
GO:0016049	cell growth
GO:0016070	RNA metabolic process
GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic