Version 5.4
Bos taurus Gene: CDK12
Summary
InnateDB Gene IDBG-639377.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDK12
Gene Name cyclin-dependent kinase 12
Synonyms CRKRS
Species Bos taurus
Ensembl Gene ENSBTAG00000013238
Encoded Proteins
IDBP-691533
cyclin-dependent kinase 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167258:
Gene Information
Type Protein coding
Genomic Location Chromosome 19:40528317-40566472
Strand Forward strand
Band
Transcripts
ENSBTAT00000002005 ENSBTAP00000002005
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0030332 cyclin binding
Biological Process
GO:0006468 protein phosphorylation
GO:0043405 regulation of MAP kinase activity
GO:0046777 protein autophosphorylation
GO:0070816 phosphorylation of RNA polymerase II C-terminal domain
Cellular Component
GO:0002944 cyclin K-CDK12 complex
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0016607 nuclear speck
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000167258
View Gene Order
ENSMUSG00000003119
View Gene Order
Cross-References
SwissProt
TrEMBL G5E518
UniProt Splice Variant
Entrez Gene 511513
UniGene Bt.67418
RefSeq NM_001205701 XM_005220717
HUGO HGNC:24224
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02049117 DAAA02049118
GenPept
RNA Seq Atlas 511513

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca