Bos taurus Gene: TSPO
Summary
InnateDB Gene IDBG-642147.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSPO
Gene Name Translocator protein
Synonyms BZRP
Species Bos taurus
Ensembl Gene ENSBTAG00000018073
Encoded Proteins
translocator protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100300:
Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:114596006-114608640
Strand Forward strand
Band
Transcripts
ENSBTAT00000024060 ENSBTAP00000024060
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
GO:0031966 mitochondrial membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Neuroactive ligand-receptor interaction pathway
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt P30535
TrEMBL
UniProt Splice Variant
Entrez Gene 281033
UniGene Bt.49341
RefSeq NM_175776
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102933 M64520
GenPept AAA30686 AAI02934
RNA Seq Atlas 281033