Version 5.4
Bos taurus Gene: EYA2
Summary
InnateDB Gene IDBG-643097.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EYA2
Gene Name Eyes absent homolog 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013336
Encoded Proteins
IDBP-695626
Eyes absent homolog 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000064655:
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may be post-translationally modified and may play a role in eye development. A similar protein in mice can act as a transcriptional activator. Alternative splicing results in multiple transcript variants, but the full-length natures of all of these variants have not yet been determined. [provided by RefSeq, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:76311439-76487993
Strand Forward strand
Band
Transcripts
ENSBTAT00000017737 ENSBTAP00000017737
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006470 protein dephosphorylation
GO:0006974 cellular response to DNA damage stimulus
GO:0007275 multicellular organismal development
GO:0014706 striated muscle tissue development
GO:0016568 chromatin modification
GO:0016576 histone dephosphorylation
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:0097345 mitochondrial outer membrane permeabilization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000064655
View Gene Order
ENSMUSG00000017897
View Gene Order
Cross-References
SwissProt Q58DB6
TrEMBL
UniProt Splice Variant
Entrez Gene 615264
UniGene Bt.26339
RefSeq NM_001035464 XM_005214851
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BT021681
GenPept AAX46528
RNA Seq Atlas 615264

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca