Bos taurus Gene: YTHDF2
Summary
InnateDB Gene IDBG-644860.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol YTHDF2
Gene Name YTH domain family protein 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015771
Encoded Proteins
YTH domain family protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198492:
This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Oct 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:125294728-125324175
Strand Reverse strand
Band
Transcripts
ENSBTAT00000020940 ENSBTAP00000020940
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0044822 poly(A) RNA binding
GO:1990247 N6-methyladenosine-containing RNA binding
Biological Process
GO:0043488 regulation of mRNA stability
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt Q0VCZ3
TrEMBL
UniProt Splice Variant
Entrez Gene 541050
UniGene Bt.40475 Bt.66143
RefSeq NM_001076253
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC119920
GenPept AAI19921
RNA Seq Atlas 541050