Version 5.4
Bos taurus Gene: CPLX2
Summary
InnateDB Gene IDBG-645067.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CPLX2
Gene Name Complexin-2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013741
Encoded Proteins
IDBP-697746
Complexin-2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000145920:
Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:5215474-5217493
Strand Reverse strand
Band
Transcripts
ENSBTAT00000018256 ENSBTAP00000018256
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0019905 syntaxin binding
Biological Process
GO:0006810 transport
GO:0006836 neurotransmitter transport
GO:0006887 exocytosis
GO:0031915 positive regulation of synaptic plasticity
GO:0043303 mast cell degranulation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0042629 mast cell granule
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000145920
View Gene Order
ENSMUSG00000025867
View Gene Order
Cross-References
SwissProt P84088
TrEMBL
UniProt Splice Variant
Entrez Gene 281711
UniGene Bt.87768
RefSeq NM_174283 XM_005211180 XM_005211181
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL D50807
GenPept BAA09434
RNA Seq Atlas 281711

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca