Bos taurus Gene: CDC25C | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Gene | IDBG-645944.3 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | CDC25C | ||||||||||||||
Gene Name | M-phase inducer phosphatase 3 | ||||||||||||||
Synonyms | |||||||||||||||
Species | Bos taurus | ||||||||||||||
Ensembl Gene | ENSBTAG00000005293 | ||||||||||||||
Encoded Proteins |
M-phase inducer phosphatase 3
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Protein Structure | |||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
Entrez Gene | |||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158402:
This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||
Type | Protein coding | ||||||||||||||
Genomic Location | Chromosome 7:51313474-51344138 | ||||||||||||||
Strand | Reverse strand | ||||||||||||||
Band | |||||||||||||||
Transcripts |
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Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||||||||
NETPATH | |||||||||||||||
REACTOME |
G2/M Transition pathway
Cyclin A/B1 associated events during G2/M transition pathway
G2/M DNA damage checkpoint pathway
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex pathway
Cell Cycle, Mitotic pathway
Mitotic G2-G2/M phases pathway
Cell Cycle pathway
Cyclin B2 mediated events pathway
G2/M Checkpoints pathway
Activation of ATR in response to replication stress pathway
Polo-like kinase mediated events pathway
Cell Cycle Checkpoints pathway
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KEGG | |||||||||||||||
INOH | |||||||||||||||
PID NCI | |||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||
NETPATH | |||||||||||||||
REACTOME |
Activation of ATR in response to replication stress pathway
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex pathway
G2/M DNA damage checkpoint pathway
Polo-like kinase mediated events pathway
Cyclin A/B1 associated events during G2/M transition pathway
Cyclin B2 mediated events pathway
G2/M Checkpoints pathway
Cell Cycle pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Mitotic G2-G2/M phases pathway
Cell Cycle Checkpoints pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
G2/M DNA damage checkpoint pathway
Cell Cycle pathway
Cell Cycle Checkpoints pathway
G2/M Checkpoints pathway
Mitotic G2-G2/M phases pathway
Cyclin A/B1 associated events during G2/M transition pathway
Activation of ATR in response to replication stress pathway
Cyclin B2 mediated events pathway
Polo-like kinase mediated events pathway
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex pathway
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KEGG |
Cell cycle pathway
Progesterone-mediated oocyte maturation pathway
Oocyte meiosis pathway
Cell cycle pathway
Progesterone-mediated oocyte maturation pathway
Oocyte meiosis pathway
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INOH | |||||||||||||||
PID NCI |
PLK3 signaling events
ATM pathway
ATR signaling pathway
PLK1 signaling events
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Cross-References | |||||||||||||||
SwissProt | A5D7P0 | ||||||||||||||
TrEMBL | |||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | 507731 | ||||||||||||||
UniGene | Bt.43933 | ||||||||||||||
RefSeq | NM_001097996 XM_005209411 XM_005209412 XM_005209413 XM_005209414 XM_005209415 XM_005209416 XM_005209417 | ||||||||||||||
HUGO | |||||||||||||||
OMIM | |||||||||||||||
CCDS | |||||||||||||||
HPRD | |||||||||||||||
IMGT | |||||||||||||||
EMBL | BC140630 | ||||||||||||||
GenPept | AAI40631 | ||||||||||||||
RNA Seq Atlas | 507731 | ||||||||||||||